A Review on Krabbe Disease

Authors

  • Palakurthi Yanadaiah Department of Pharmacy Practice, Sun Institute of Pharmaceutical Education and Research, Kakupalli (V), Nellore Rural (M), SPSR Nellore (Dist) - 524346, Andhra Pradesh, India https://orcid.org/0000-0001-6117-8564
  • Kotloni Sreekanth Sun Institute of Pharmaceutical Education and Research, Kakupalli (V), Nellore Rural (M), SPSR Nellore (Dist) - 524346, Andhra Pradesh, India
  • Challa Likhitha Sun Institute of Pharmaceutical Education and Research, Kakupalli (V), Nellore Rural (M), SPSR Nellore (Dist) - 524346, Andhra Pradesh, India
  • Chandana Chinthimi Sun Institute of Pharmaceutical Education and Research, Kakupalli (V), Nellore Rural (M), SPSR Nellore (Dist) - 524346, Andhra Pradesh, India

DOI:

https://doi.org/10.26452/fjphs.v3i1.352

Abstract

Krabbe disorder was autophagosome collection disorder leading to gradual as well as eloquent neurodegenerative. Immature, childish, and individual types of Krabbe disorder have already been defined as ignorant, one of the most typical. Kids, including an infant, usually appear regularly from newborns and proceed to overlook the development stages within six months of aging and death within 2-3 years of life. Krabbe's disorder was the epistemology of dysfunction with acid hydrolase galactosyl ceramidase. Therapeutic approaches, including enzyme replacement, surface reduction, enzymatic activity chaperones, and genetic engineering, have already shown promise in LSDs. The success in recent years of combinational treatment strategies in minor mammal models like Krabbe disorder and the detection of early identification pathogenic methodologies focus on providing optimism again for developing more effective therapeutic interventions for this severe disease. The above study provided a quick background like Krabbe disorder & transformation like single and combined effect treatment interventions and described novel infective methods and how they may affect the event of further practical therapeutic approaches.

Keywords:

Blood and Blood Products Cell Leukodystrophy, Krabbe Disorder, Lysosomal Collection Disorder

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Published

2023-01-18

How to Cite

Palakurthi Yanadaiah, Kotloni Sreekanth, Challa Likhitha, & Chandana Chinthimi. (2023). A Review on Krabbe Disease. Future Journal of Pharmaceuticals and Health Sciences, 3(1), 98–103. https://doi.org/10.26452/fjphs.v3i1.352

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Review Articles

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