Determination of Ergotamine Tartrate and Caffeine Simultaneously in their Formulation


  • Srikanth A Department of Pharmaceutical Analysis, Vasavi Institute of Pharmaceutical Sciences, Vasavi Nagar, Peddapalli (Village), Sidhout (Mandal), Kadapa (Dist) - 516247, Andhra Pradesh, India
  • Bhavanasi Mounika Department of Pharmaceutical Analysis, Sri Padmavathi Mahila Visvavidyalayam, Padmavathi Nagar, Tirupati – 517502, Andhra Pradesh, India
  • Vonteru Muni Sekhar Department of Pharmaceutical Analysis, Vagdevi College of Pharmacy and Research Centre, Brahmadevam Village, Muthukur Mandal, SPSR Nellore - 524 346, Andhra Pradesh, India



Ergotamine Tartrate, Caffeine


There are numerous additional benefits of caffeine, and the most popular one is to increase mental alertness. For the treatment of migraine headaches, caffeine is taken orally or injected together with ergotamine and medicines such as aspirin and acetaminophen. A group of drugs known as ergot alkaloids includes ergotamine. It acts in conjunction with coffee by inhibiting the enlargement of blood vessels in the head that cause headaches. Specific forms of headaches are treated or prevented with this combination of medications (vascular headaches, including migraine and cluster headaches). The UV-Visible Spectrophotometric technique for simultaneous assessment of caffeine and ergotamine in the tablet dosage form in the solvent system of methanol and distilled water in a 1:1 ratio provides an accurate estimate of the % label claim of a marketed product (Cafergot).


Download data is not yet available.



How to Cite

Srikanth A, Bhavanasi Mounika, & Vonteru Muni Sekhar. (2023). Determination of Ergotamine Tartrate and Caffeine Simultaneously in their Formulation. Future Journal of Pharmaceuticals and Health Sciences, 3(1), 1–4.



Original Articles