Physicochemical, Phytochemical Screening and Evaluation of Antidiabetic Activity of Ficus dalhousiae Fruits on Alloxan Induced Diabetic Rats

Abstract

The aim of the present study was to evaluate Physicochemical, Phytochemical Screening of Antidiabetic Activity of Ficus dalhousiae Fruits in Alloxan Induced Diabetic Rats. A plant material like “Ficus dalhousiae” member of the genus Moraceae, and physico chemical standards used for ash values. In statistical analysis, all data were represented in mean ± SEM (Standard error mean) values expressed as mean ± SEM of six samples data were analysed by one-way ANOVA followed by Dunnett's test. Effect of extracts of Ficus dalhousiae fruit on blood parameters against Alloxan induced Diabetic rats. The Physico-chemical standards of the fruit of Ficus dalhousiae have been carried out. The result shows that total Ash value was 6.7% w/w, water in soluble Ash 2.5% w/w and acid insoluble ash 0.7 w/w. Moisture content was 14.74% w/w. The water-soluble extractive values were 1.2%w/w, alcohol soluble extractive, Values 1.6% w/w and chloroform soluble extractive values were 4.6% w/v. Foaming index was 100., Fat content was 120mg, resin content was 250 mg, chloroform extract yield Was 4.3% w/w. In the present study alloxan administration induced a pronounced increase in the concentration of blood glucose and decreased glycogen in liver and muscles. A significant hyperglycaemia was attained with 24 hours after alloxan administration. The maximum effect was produced after 5 days.