RP-HPLC Method Development and Validation for the Simultaneous Estimation of Ivermectin and Albendazole in its Pure and Combine Dosage Form

Abstract

That whole percentage purification of ivermectin and albendazole seemed to be noticed of being 101.04% and 99.24% in both. That whole stability studies specifications just that Ivermectin and Albendazole also including theory trays or trying to chase aspect have been discovered of about be 4668, 1.3 and 6089 and 1.2, the resolving seemed to be discovered to also be 6.0. This same methodological approach must of been conclusively proven well according to aspect of this approach (ICH, Q2 (R1)). This same simple linear regression survey adjuvant but rather antifungal medication must have been present in concentration after all 50µg-250µg and 5µg-50µg as well as linkage coefficient (r²) has been encountered to really be 0.999 and 0.999, % regeneration had been noticed of about be 99.56% and 99.47%, %RSD regarding predictive validity had been 0.2 and 0.2, % RSD regarding medium accuracy must have been 0.2 and 0.1 respectively. It and accuracy analyze seemed to be exact, comprehensive, as well as consistent LOD value was 3.17 and 5.80, and LOQ value was 0.0172 and 0.212 respectively. Thus the posited RP-HPLC technique will be used for regimen assessment sure Ivermectin and Albendazole in API and Pharmaceutical dosage form.