Evaluation of In-Vitro Cytotoxic Potential of Ficus benghalensis Tender Prop Roots Extract

Authors

  • Badugu Kranti Kumar Department of Pharmacognosy, St. Mary's Group of Institutions, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist)-508284, Telangana, India http://orcid.org/0000-0003-0320-9603
  • Kondoju Arun Kumar Chary St. Mary's Group of Institutions, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist)-508284, Telangana, India http://orcid.org/0000-0003-3490-465X
  • Kiran St. Mary's Group of Institutions, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist)-508284, Telangana, India http://orcid.org/0000-0003-3587-4843
  • Gajarlu Shivani St. Mary's Group of Institutions, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist)-508284, Telangana, India http://orcid.org/0000-0001-7778-5983
  • Abdul Rahaman S K St. Mary's Group of Institutions, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist)-508284, Telangana, India
  • Boidi Mamatha St. Mary's Group of Institutions, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist)-508284, Telangana, India http://orcid.org/0000-0002-4227-2448

DOI:

https://doi.org/10.26452/fjphs.v2i3.275

Keywords:

Colon Adenocarcinoma, Colo 320 Cell Lines, Tryphan Blue Assay, MTT Assay

Abstract

Cancerous cell lines might grow to develop a kind indispensible interconnect within stages through the structure–based drug to a collection of medical applicants such as cancer therapeutics. The current study is one such effort to screen for in vitro cytotoxic potential of methanolic prop root extract of Ficus benghalensis against human colon adenocarcinoma (Colo 320) cell cultures besides Tryphan turquoise assay as well as MTT microarrays following the 24 hours exposure. A present work demonstrated a reduction in the count of total viable cell by Tryphan blue assay. However, we have reported anti-proliferative potential of methanolic extract of Ficus benghalensis on colo 320 cell cultures with just an Ic50 values like 87.03µg/milliliter. Extensive research needs to be employed in the near future to explore the anti cancer potential of various solvent extracts of different parts of the plant to evolve a molecule of interest.

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Published

2022-06-15

How to Cite

Badugu Kranti Kumar, Kondoju Arun Kumar Chary, Kiran, Gajarlu Shivani, Abdul Rahaman S K, & Boidi Mamatha. (2022). Evaluation of In-Vitro Cytotoxic Potential of Ficus benghalensis Tender Prop Roots Extract. Future Journal of Pharmaceuticals and Health Sciences, 2(3), 159–169. https://doi.org/10.26452/fjphs.v2i3.275

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