Formulation and Evaluation of herbal ointment to treat psoriasis with Indigofera aspalathoides

Abstract

The current study aims to prepare an herbal ointment using several extracts of the complete Indigofera aspalathoides plant and assess the extracts' antimicrobial effectiveness for psoriasis. The entire plant's morphological and physiochemical characteristics were evaluated. Different extracts of powdered whole plant were made, and these extracts underwent phytochemical analysis. Alkaloids, carbohydrates, flavonoids, steroids, and other phytoconstituents were all present in the ethanolic extract. The extract's antimicrobial activity was examined throughout. Even at low concentrations, the ethanol and acetone extracts demonstrated promising efficacy and a maximum zone of inhibition. The antifungal activity of the ethanolic extract was assessed at 4%w/w and 2%w/w concentrations in an ointment formulation. The antifungal activity of the ointment made with ethanolic extract was on par with that of regular clobetasol cream. The ethanol extract cream's activity was shown to outperform that of the typical ointment.