C-Reactive Protein as a Useful Marker for Guiding the Duration of Antibiotic Therapy in Neonatal Sepsis

Authors

  • Nizamuddin N D Department of Pharmaceutical Chemistry, St John's College of Pharmaceutical Sciences, Yerrakota, Yemmiganur, Kurnool District, Andhra Pradesh, India
  • Deepthi K Department of pharmacy practice, St John's College of Pharmaceutical Sciences, Yerrakota, Yemmiganur – 518 360, Kurnool Dist, Andhra Pradesh, India
  • Ashmat Banu S Department of pharmacy practice, St John's College of Pharmaceutical Sciences, Yerrakota, Yemmiganur – 518 360, Kurnool Dist, Andhra Pradesh, India
  • Vageesh N M Department of Pharmaceutics, St John's College of Pharmaceutical Sciences, Yerrakota, Yemmiganur – 518 360, Kurnool Dist, Andhra Pradesh, India
  • Mallikarjuna Reddy Y Bhavana Hospital, Adoni – 518 301, Andhra Pradesh, India

DOI:

https://doi.org/10.26452/fjphs.v3i2.459

Keywords:

C-reactive protein, Neonatal Sepsis, Prevalence, Incidence, Duration of therapy, Neonatal intensive care unit (NICU)

Abstract

Septicaemia is a clinical manifestation best described besides signs or symptoms like an infectious disease, both with and without, usually accompanied by stringent in the very first month after birth. A . C - reactionary transcription factor test will measure the quantity of crp inside the fluid versus identifying inflammatory causes and acute requirements or even supervise the same consequences like disorder through chronic health conditions. This study was conducted to describe and obtain data about prevalence, incidence during admission, associated risk factors, and duration of antibiotic therapy in respiratory tract infections.Some prospective longitudinal survey was performed in a children's health center over six years. In Group A (Neonatal Sepsis), 17 had CRP value> 10 mg/l duration of therapy was < 7 days with 2 relapses observed. In Group- B (Risk factors), 27 patients for > 11 days of therapy with 1 relapse were observed. The duration of antibiotics should be based on the severity and specificity of neonatal infection analyzed by CRP Values to facilitate the rational use of antibiotics providing optimal care. First, from the findings of this study, that can be concluded that the said plasma cholesterol CRP value systems used to have moderate responsiveness throughout respiratory tract infections, and therefore universal asynchronous receiver plasma cholesterol CRP value systems alone are enough to have been used as a parametric such as trying to guide this same length of time like antimicrobial therapy in some kind of a team like newborn babies as well as the presumed newborn's infectious disease.

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Published

2023-06-21

How to Cite

Nizamuddin N D, Deepthi K, Ashmat Banu S, Vageesh N M, & Mallikarjuna Reddy Y. (2023). C-Reactive Protein as a Useful Marker for Guiding the Duration of Antibiotic Therapy in Neonatal Sepsis. Future Journal of Pharmaceuticals and Health Sciences, 3(2), 235–245. https://doi.org/10.26452/fjphs.v3i2.459

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