A Simple UV-Vis Spectrophotometric Assay study on different brands of Mefenamic Acid, Paracetamol and Furosemide

Authors

  • Sayyed Nazifa S Ali-Allana College of Pharmacy, Akkalkuwa-425415, Nandurbar, Maharashtra, India
  • Patel Seema A Ali-Allana College of Pharmacy, Akkalkuwa-425415, Nandurbar, Maharashtra, India
  • Manjra Mehfuza U Ali-Allana College of Pharmacy, Akkalkuwa-425415, Nandurbar, Maharashtra, India
  • Lajporiya Mobina I Ali-Allana College of Pharmacy, Akkalkuwa-425415, Nandurbar, Maharashtra, India
  • Aejaz Ahmed A Department of Pharmaceutical Chemistry, Ali-Allana College of Pharmacy, Akkalkuwa-425415, Nandurbar, Maharashtra, India https://orcid.org/0000-0002-7552-877X
  • Khan G J Ali-Allana College of Pharmacy, Akkalkuwa-425415, Nandurbar, Maharashtra, India
  • Quazi Majaz Ali-Allana College of Pharmacy, Akkalkuwa-425415, Nandurbar, Maharashtra, India https://orcid.org/0000-0001-8632-6295
  • Patel M Siddik Ali-Allana College of Pharmacy, Akkalkuwa-425415, Nandurbar, Maharashtra, India

DOI:

https://doi.org/10.26452/fjphs.v2i2.216

Keywords:

Ultra Violet-Visible Spectrophotometer, Furosemide, Paracetamol, Mefanamic Acid, Method Development, Assay

Abstract

The objective of the project seeks to develop an effective significant less going to consume as well as simple spectrophotometry for such assay of Mefenamic acid Paracetamol and Furosemide. Comparative of assay of 3 distinct brand products of Mefenamic acid (Meftal 250-dt, Mefacid, Mefac), Paracetamol (T-98, Parawal-500, Crocin) and Furosemide (Lasix, Frusenex, and Furosemide) available in medical store of Akkalkuwa dist-nandurbar, India has also been done. With us results reveal that between the all 3 brand products anyway of Mefac shows highest percent assay 105.48% while mefacid shows lowest value for percentage assay 95.48% and in all brands of Paracetamol Parawal-500 shows highest percent assay 106.66% T-98 shows lowest percent assay 98.66% & Furosemide Frusenex shows greatest percentage assay of 104% while Furosemide demonstrates lower critical for percentage assay 95%. The part of its success excellent reliability inside the variety of 6.25-100 µg/ml with all brands of Mefenamic acid and Furosemide to correlation coefficient of 0.999. The recovery among all brand products of Mefenamic acid, Paracetamol and Furosemide was > 90%. The dilution and assay method perform in water and NaOH as a solvent.

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Published

2022-03-15

How to Cite

Sayyed Nazifa S, Patel Seema A, Manjra Mehfuza U, Lajporiya Mobina I, Aejaz Ahmed A, Khan G J, Quazi Majaz, & Patel M Siddik. (2022). A Simple UV-Vis Spectrophotometric Assay study on different brands of Mefenamic Acid, Paracetamol and Furosemide. Future Journal of Pharmaceuticals and Health Sciences, 2(2), 57–62. https://doi.org/10.26452/fjphs.v2i2.216

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