A Glimpse of the Molecule Chalcone

Abstract

The compound chalcone is very common which can available by synthetic means and naturally occurring from plant sources. These compounds have predominant value for their abundant properties with less adverse impacts on biological systems. The naturally occurring chalcone belongs to the flavonoid family. Chalcones are structural with two aromatic rings connected with three carbon alpha & beta unsaturated carbonyl systems. They possess many pharmacological activities like anti-inflammatory, antimalarial, antifungal, antileishmanial activities based on the substituents substituted on them. Benzene rings containing conjugated double bonds and completely delocalized pi electron system, molecules possessing this system have low redox potential and greater electron transfer reactions. This review article covers the chemistry, synthesis, biological activities, Isolation of natural or synthesized derivatives of chalcone. The main entity of this article is to summarize the expansion of this molecule related to the structural entities and pharmacological actions.