In vitro evaluation of anti-ulcer activity of ethyl acetate extract of Strychnos wallichiana roots

Abstract

Strcychnos wallichiana is a native plant that has been used extensively in traditional medicine to cure a variety of ailments. The current study aimed to show the ethyl acetate extract of Strcychnos wallichiana's in-vitro anticancer activity. The inhibitory activity of in-vitro H?-K? ATPase was assessed. The spectrophotometric analysis of H?-K? ATPase inhibitory activity. The outcome was expressed as an ethyl acetate extract of Strcychnos wallichiana that contained alkaloids, steroids, tannins, and phenolic compounds and that, when used at a concentration of 100 g/ml, had a proton pump inhibitory action comparable to that of omeprazole on goat stomach mucosal homogenate. The results of the observations suggested that Strcychnos wallichiana might be helpful in the treatment of stomach ulcers.