Pancha Paashaana Chendhooram: Standardization, Characterization, and Instrumental Analysis of a Potential Anti-Cancer Herbal Mineral Formulation

Abstract

Cancer is a condition marked by unchecked or unregulated cell proliferation that can spread to other organs via lymphatic and blood vessels. The leading cause of death for both men and women worldwide is cancer. Using traditional Siddha literature as our guide, we have established how to prepare Pancha Paashaana Chendooram (PPC), a Siddha compound herbal-mineral therapy for treating oral cancer. The physicochemical characterization of the Siddha herbal-mineral formulation PPC was the goal of the current investigation. The physicochemical properties were examined, including ash values, loss on drying, pH, and flame test, in addition to solubility. The entire cinder analysis was negative, and the pH assessment was 7.3 with a reduction of drying at 102±2 oC of 0.133% w/w. The sample PPC's SEM analysis revealed the presence of nano- also near-nanoparticles. According to the quantitative examination, the medicine contained nitrate, iron, mercury, arsenic, sulfur, and other minerals. FT-IR spectroscopy, XRF and EDX were studied in this work. The studies revealed that PPC has equal chemical opulence and mineral richness. For the cure for an array of illnesses and disorders, the Indian Siddha medicinal organization regularly used A. indica, P. betle, G. herbaceum, E. axillarem, O. sanctum, P.deamia, with P.nodiflora. The antioxidant action with antibacterial movements of water concentrates of the dried leaves was evaluated in this work using in vitro traditional techniques employing sparkling leaves of the cited herbals. This PPC is also having multiple actions in Anti-Rheumatic, Anti- Inflammatory, Analgesic, Anti- Histamine, and Anti- Pyretic illnesses.