Formulation and Evaluation of Phytosome and Plants Exhibiting Anti-Inflammatory Activity

Abstract

The aim of the present study is formulation & evaluation of phytosome complexes from plant extracts of Ixora coccinea, Chrysanthemum morifolium & Tinospora cordifolia. Plants exhibiting anti-inflammatory activity (Ixora coccinea, Chrysanthemum morifolium, and Tinospora cordifolium) were selected. To carry out the Cold maceration process, prepare an aqueous and alcoholic extract of Ixora coccinea, Chrysanthemum morifolium, and Tinospora cordifolia. To perform Phytochemical screening, phytochemical evaluation, and FTIR spectral analysis. To prepare phagosomes by cholesterol complex method. Optimization of phagosomal formulations. The in vitro drug release from F1 to F9 was preserved in table below. It is executed that 8-hour drug releases time profile From the results, it was reported that F1 formulation preparation using Ixora coccinea exhibited 19.9% of drug release, which is less than 30%, indicating that worst release was not observed. This is the desired characteristic to be passed by the control release formula. At the end of the 4th hour, 48.9 % of drug release was observed 98.7% of Drug was released at the end of the 8th hour.