Comparative study of pregabalin and carbamazepine in painful diabetic peripheral neuropathy at the tertiary care hospital

Abstract

This study aimed to examine the effectiveness of carbamazepine as well as pregabalin in lowering the degree of pain associated with diabetic peripheral neuropathy. The results revealed noteworthy insights into the comparative effectiveness of these medications. Pregabalin, as a calcium channel modulator, has demonstrated efficacy in numerous neuropathic pain conditions. Beyond pain reduction, these drugs influence various aspects of daily functioning, emotional well-being, and social interactions is crucial for tailoring treatment approaches. The discussion explores Pregabalin medication stands out in improving overall quality of life of the patients. The results presented here indicated that among diabetic patients, age, HbA1c, DR, and the duration of their diabetes are related to considerably higher risks of DPN; however, BMI, smoking, TG, as well as TC did not show any evidence of an increased risk of DPN. The results of the study offer a scientific foundation for a deeper comprehension of the causes of peripheral neuropathy-complicated type 2 diabetes and the outcomes of preventative measures.Bottom of Form