Biological activity of newly synthesised compounds of 2-(3-oxo-2, 3-dihydro-4H-benzo [b] [1,4] oxazin-4-yl)-N-substituted phenyl acetamide and its derivatives
DOI:
https://doi.org/10.26452/ijcpms.v2i1.256Keywords:
In vitro Anti-Proliferative Activity, Human Cancer Cells, Cell GrowthAbstract
In vitro antiproliferative activity of the newly prepared synthetic compounds of 2 - ( 3 – oxo - 2, 3 – dihydro – 4 H – benzo [b] [1,4] oxazin – 4 - yl) - N-substituted phenyl acetamides (8a-j) were evaluated against four different human cancer cell lines, MIAPACA (pancreatic), HeLa (cervical), IMR32 (neuroblastoma) MDA-MB-231 (breast) and IMR32 (neuroblastoma) summarized in Table below. The compounds 8g and 8i were more active than the remaining compounds.
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Published
2022-01-28
How to Cite
Balakrishna Reddy B, & Jagan Mohan Gopisetti. (2022). Biological activity of newly synthesised compounds of 2-(3-oxo-2, 3-dihydro-4H-benzo [b] [1,4] oxazin-4-yl)-N-substituted phenyl acetamide and its derivatives. International Journal of Clinical Pharmacokinetics and Medical Sciences, 2(1), 14–17. https://doi.org/10.26452/ijcpms.v2i1.256
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