Evaluation of Natural Polysaccharides as Biodegradable Polymers for Colon Specific Drug Delivery

Authors

  • Voleti Vijaya Kumar Department of Pharmaceutics, School of Pharmacy, Sathyabama Institute of Science and Technology, Chennai, Tamilnadu, India
  • Nandhini M Department of Pharmacy Practice, School of Pharmacy, Sathyabama Institute of Science and Technology, Chennai, Tamilnadu, India
  • Shanmugapandiyan P Department of Pharmaceutical Chemistry, School of Pharmacy, Sathyabama Institute of Science and Technology, Chennai, Tamilnadu, India
  • Bhagya Buela Department of Pharmaceutics, Shadan Women's College of Pharmacy, Khairatabad, Hyderabad, Telangana, India

DOI:

https://doi.org/10.26452/ijcpms.v3i1.480

Keywords:

Prednisolone, Tamarind Seed Polysaccharide (TSP), Guar Gum, Colon Targeting

Abstract

The present data analysis has been conducted to examine this same property of natural oligosaccharides to behave as just a degradable delivery company for such colon particular drug delivery and attempt were made of between establish pharmaceutical formulations utilizing tamarinds seeds oligosaccharides but also hydrophilic polymer just like percentage trying to control polymeric materials, that also necessary attempting to prevent this same release of drug within top side build systems but also has shown the discharge this same drug inside the colon even by photosynthetic bacteria deterioration. Steroid inhalers were being used as someone synthesized compounds, which would be androgenic steroids anti-inflammatory drugs used in the diagnosis like inflammatory bowel diseases. This same vitro cell release of drug finding indicates a certain pharmaceutical formulation able to prepare besides tamarind seeds oligosaccharides displayed improved comparable results as for hydrophilic polymer. this also demonstrated a certain mango seed carbohydrate convey almost all of the drug towards the colon as well as severely limits the discharge of something like the drug within top side build systems. So, although, steroid inhalers formulas didn't discharge the drug through gastrointestinal system, even though produced drug towards the bowel leading to delayed permeability of both the drug but also attempting to make drug accessible such as regional and local within the intestines.

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Published

2023-02-03

How to Cite

Voleti Vijaya Kumar, Nandhini M, Shanmugapandiyan P, & Bhagya Buela. (2023). Evaluation of Natural Polysaccharides as Biodegradable Polymers for Colon Specific Drug Delivery. International Journal of Clinical Pharmacokinetics and Medical Sciences, 3(1), 29–34. https://doi.org/10.26452/ijcpms.v3i1.480

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Original Article