Urolithiasis: A Clinical Review

Authors

  • Tholla Bhagyamma Department of Pharmacology, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati-517503, Chittoor (Dist), Andhra Pradesh, India https://orcid.org/0000-0001-5820-1823
  • Bandi Haripriya Department of Pharmacology, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati-517503, Chittoor (Dist), Andhra Pradesh, India
  • Kishore Bandarapalle Department of Pharmaceutics, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati-517503, Chittoor (Dist), Andhra Pradesh, India https://orcid.org/0000-0003-0032-4331
  • Kammapalli Ganesh Department of Pharmacology, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati-517503, Chittoor (Dist), Andhra Pradesh, India https://orcid.org/0000-0001-6976-1594
  • Kokkarla Vyshnavi Department of Pharmacology, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati-517503, Chittoor (Dist), Andhra Pradesh, India
  • Dondapati Tejaswi Department of Pharmaceutics, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati-517503, Chittoor (Dist), Andhra Pradesh, India https://orcid.org/0000-0002-1520-5303

DOI:

https://doi.org/10.26452/ijcpms.v2i3.331

Abstract

Renal calculi are a critical concern in both India and developing markets. 12% of the planet's population is plagued only by urology ailments, which is on the upswing. Renal calculi are predominant in both men and women. Renal calculi's multifaceted genesis has thus far been linked to a heightened risk of end-stage nephrotic syndrome. Renal calculi ultimately impact the actions of the urethral and ureters. The much more prevalent kind of renal calculi would seem to be calcium oxalate and the one that creates at Randall's Plaque on the renal papillary surfaces. The far more prominent calculi investigated in India are all those triggered by calcium oxalate in kidneys. Various physic-chemical variables drive the perplexing in calculi creation, besides polymer concentration, polymerization, propagation, consolidation, and lull of urinary calculi elements within renal tubules. No medication could efficiently and successfully alleviate renal calculi or prevent them from arising back. Recurrence inhibition is vital for creating more remedies, which calls for a greater understanding of the phenomena driving calculi creation. With the aid of this data, allied health professionals, highly skilled medical, and internists might easily comprehend the inception and recurrence of renal calculi and contemplate new avenues of investigation.

Keywords:

Renal Calculi, Epidemiology, Pathogenesis, Diagnosis, Management

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Published

2022-08-10

How to Cite

Tholla Bhagyamma, Bandi Haripriya, Kishore Bandarapalle, Kammapalli Ganesh, Kokkarla Vyshnavi, & Dondapati Tejaswi. (2022). Urolithiasis: A Clinical Review. International Journal of Clinical Pharmacokinetics and Medical Sciences, 2(3), 115–124. https://doi.org/10.26452/ijcpms.v2i3.331

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Review Article

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