Efficiency of an Ethanol Extract of Alpinia Purpurata L. Leaves in Wound Healing of Diabetic Rats

Abstract

In the current research, it was investigated if Alpinia purpurata L., a member of the ginger family (Zingiberaceae), could be utilised to treat wounds. Using excision and burn wound models, the efficacy of Alpinia purpurata ethanolic leaf extract in rat wound healing was assessed. When compared to the control group, which had a wound area of 29%, the animals treated with the extract demonstrated reductions in the wound area of 74% and 93%, respectively (5% and 10%w/w). In the excision model, it was discovered that wounds treated with extract epithelialized and contracted more quickly than control wounds. Histopathological research provided more support for this. Studies on wound contractions show that they rise in direct proportion to the amount of herbal extracts present. Both variants come with mupirozin already inserted. In diabetic rats, Alpinia purpurata greatly speeds up wound healing; additional research into this effect in humans is advised.