A Review on chemotherapy induced toxicities: Challenges in their management

Abstract

One of the reasons behind the chemotherapeutic drugs that differentiate from other drugs is the toxic effects. Toxicity is the main concern for chemo drugs. These drugs usually have a narrow therapeutic range and responsible for unwanted toxic effects. These toxic effects constitute a considerable endpoint for pharmacodynamic studies of cytotoxic drugs. Toxic effects may vary depending upon the dose, term of usage, and individual susceptibility. The management of these toxicities should be given the utmost importance to better their health and to improve their tolerability. By conscious of the toxicity of independent regimens assist the physicians to pick out patients requiring supportive therapy or reduced toxic regimens. Any measure that aid to lessen the phenomenon or seriousness of toxicities in patients going on chemotherapy, would be favorable and amplify the patient’s standard of living. This article offers an overview of toxicities and their management of chemotherapeutic drugs.