evaluation of cardioprotective activity of centella asiatica l on experimentally induced oxidative stress

Abstract

Nowadays, lifestyle and food habits have resulted in many complaints, leading to an increasing interest in identifying natural phytochemical compounds from plant species that can be used as medicines without significant side effects. Herbal medicines are multicomponent mixtures of organic and inorganic compounds, and their chemical constituents possess a pharmacological and antioxidant potential that could have the ability to protect vital organs from several ailments with less or no toxic Effect. The Present study aimed to evaluate the pharmacological and antioxidant activity of the well-known medicinal plant Centella Asiatica, which was extracted traditionally. The natural antioxidants in the aqueous plant extracts ameliorate liver and heart damage by consuming ethanol. Hence, this study concluded that the aqueous Extract of Centella Asiatica profoundly protected the vital organs. These findings support the fact that the active principles of Centella Asiatica significantly contributed to the authenticity of the development of new drugs that could alleviate society from many diseases due to oxidative stress by alcohol consumption. It is essential to evaluate the pharmacological properties, and the experimentation would be necessary to standardize and elucidate the exact mechanism of action and toxicity studies of the bioactive compounds present in aqueous Extract to be formulated as protective drugs to treat the alcoholics without any side effects.