Utilising the Ethanolic Extracts of Leaves Garcinia Cambogia and Commiphora Mukul Herbal Pills Prepared for Treating Anti-Obesity Effects

Authors

  • Chandana Pasupuleti Department of Pharmaceutics, St. Mary's group of institution, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India https://orcid.org/0009-0001-7783-1895
  • Chimata manisha St. Mary's group of institution, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India https://orcid.org/0000-0002-8752-678X
  • Suraj choudhary St. Mary's group of institution, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India https://orcid.org/0009-0004-6306-3516
  • Singaram neeraj St. Mary's group of institution, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India https://orcid.org/0009-0001-4557-4767
  • Eerankadi Anusha St. Mary's group of institution, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India https://orcid.org/0000-0002-8014-0876
  • Sakil ahammed mullah St. Mary's group of institution, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India
  • Mohd ubaid ullah khan St. Mary's group of institution, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India

DOI:

https://doi.org/10.26452/ijebr.v2i1.484

Keywords:

Commiphoramukul, Garcinia cambogia, Ethanolic extract of leaves, Wet granulation

Abstract

A complex disorder called obesity is characterised by an excessive quantity of bodily fat. It raises the risk of developing other illnesses and medical conditions like diabetes, high blood pressure, and heart conditions. When our BMI is 30kg/m2 or greater, obesity is considered to exist. Today, more ailments are treated with traditional medicines—mostly herbal in nature—than with allopathic drugs. Compared to herbal drugs, allopathic drugs have higher side effects. The purpose of the current work is to create and assess the herbal tablet prepared using an ethanolic extract of Commiphoramukul and Garcinia cambogia leaves. Wet granulation was used to manufacture the formulation. Both the pre-compression parameter and the post-compression parameter of the prepared formulation were assessed. The calculation demonstrated that the permissible pre- and post-compression parameter is within bounds. Before and after the IEC's stability investigation, the Garcinia cambogia (HCA) content assay yielded results of 49.78% and 49.69%, respectively (Ion Exchange Chromatography). The content of Commiphoramukul (guggulsterones) was 12.38% and 12.26% before and after the UV Spectrophotometer stability investigation. The formulation was found to be reasonably stable based on the findings.

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Published

2023-03-31

How to Cite

Pasupuleti, C., manisha, C., Suraj choudhary, Singaram neeraj, Eerankadi Anusha, Sakil ahammed mullah, & Mohd ubaid ullah khan. (2023). Utilising the Ethanolic Extracts of Leaves Garcinia Cambogia and Commiphora Mukul Herbal Pills Prepared for Treating Anti-Obesity Effects. International Journal of Experimental and Biomedical Research, 2(1), 33–40. https://doi.org/10.26452/ijebr.v2i1.484

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Original Article