Solid Lipid Nanoparticles: A Novel Method to Drug Delivery Formulation

Abstract

Solid lipid nanoparticles, which have numerous powerful advantages for clinical therapy, drug transportation, investigation, and an extensive array of many other fields of science, are at the forefront of a quickly developing field of nanotechnology. Lipid nanoparticles also have the potential to contribute to the creation of novel therapeutics because of their unique size-dependent properties. Opioids can now be added to nanocarriers, creating an unknown drug delivery prototype that could be used for therapeutic targeting at the secondary and tertiary levels. So, because solid lipid nanoparticles have great potential for attaining the goal of controlled and site-specific drug delivery, researchers are particularly interested in them. This paper examines a variety of solid lipid nanoparticles and discusses their advantages, disadvantages, and potential remedies. The various lipid-based stable nanocarriers, including lipid drug conjugates, solid lipid nanoparticles, and nanostructured lipid carriers, are presented along with their structural variations. Solid lipid nanoparticles can be produced in various ways and for multiple purposes on a large scale. The appropriate analytical techniques for characterizing stable lipid nanoparticles are highlighted, such as scanning electron microscopy, photon correlation spectroscopy, and differential scanning calorimetry. Additionally taken into account are the solid lipid nanoparticle delivery strategy and biodistribution. Stable lipid nanoparticles could completely alter how complex diseases are treated if thoroughly investigated.