Formulation and Evaluation of Transdermal Film of Nitroglycerin

Authors

  • Arava Vidyadhari Department of Pharmacology, Saastra College of Pharmaceutical Education & Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India https://orcid.org/0000-0003-3815-7612
  • Guduru Rajeswari Department of Pharmacology, Saastra College of Pharmaceutical Education & Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India https://orcid.org/0000-0002-5221-7602
  • Dodda Chinni Krishna Reddy Saastra College of Pharmaceutical Education & Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India https://orcid.org/0000-0003-2834-8482
  • Gangala Sudarsana Saastra College of Pharmaceutical Education & Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India https://orcid.org/0000-0003-4756-5538
  • Gundala Mamatha Saastra College of Pharmaceutical Education & Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India https://orcid.org/0000-0003-1205-5861
  • Kuramutla Sisindri Saastra College of Pharmaceutical Education & Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India https://orcid.org/0000-0002-2435-6955
  • Podili Swarna Latha Saastra College of Pharmaceutical Education & Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India https://orcid.org/0000-0002-6338-174X
  • Ramakkagari Sandhya Rani Saastra College of Pharmaceutical Education & Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India https://orcid.org/0000-0001-9856-301X
  • Shaik Shajiya Taslim Department of Pharmacology, Saastra College of Pharmaceutical Education & Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India https://orcid.org/0000-0002-9079-622X

DOI:

https://doi.org/10.26452/fjphs.v1i1.56

Keywords:

Nitroglycerin, HPMC, Ethyl Cellulose, Cellulose Acetate Phthalate

Abstract

The aim of the present study was to prepare and evaluate transdermal Films of Nitroglycerin using HPMC, Cellulose acetate phthalate, ethyl cellulose and Polypropylene glycol as a rate controlling membranes and HPMC, Cellulose acetate phthalate, ethyl cellulose as drug reservoir gels. Transdermal Films of Nitroglycerin with HPMC, Cellulose acetate phthalate, ethyl cellulose by varying the blend ratios were prepared by solvent casting method. The thickness medium range between 0.18 ± 0.02 mm to 0.22 ± 0.03mm whatever signifies that they’re military uniform in thickness. The customized formulation NF1 acquires stability reports for one to three months and the general films were tested for drug content and In-vitro diffusion.

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Published

2021-03-31

How to Cite

Arava Vidyadhari, Guduru Rajeswari, Dodda Chinni Krishna Reddy, Gangala Sudarsana, Gundala Mamatha, Kuramutla Sisindri, Podili Swarna Latha, Ramakkagari Sandhya Rani, & Shaik Shajiya Taslim. (2021). Formulation and Evaluation of Transdermal Film of Nitroglycerin. Future Journal of Pharmaceuticals and Health Sciences, 1(1), 37–42. https://doi.org/10.26452/fjphs.v1i1.56

Issue

Vol. 1 No. 1 (2021): Volume 1 Issue 1

Section

Original Articles

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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