Analytical Validation and Simultaneous Estimation of Cefixime and Ornidazole by RP-HPLC Method

Authors

  • Banothu Srikanth Department of Pharmaceutical Analysis & Quality Assurance, St. Mary’s Pharmacy College, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India
  • Aaysha Firdose St. Mary’s Pharmacy College, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India
  • Muna St. Mary’s Pharmacy College, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India
  • Mubarak Ibrahim Ahmed Mohamed St. Mary’s Pharmacy College, Deshmukhi (Village), Pochampally (Mandal), Yadadri Bhuvanagiri (Dist), Telangana-508284, India

Abstract

Suitability, linearity, Precision, Accuracy method perform as the Analytical validation and simultaneous estimate consisting of the Cefixime and Ornidazole. The retention time & % RSD of Cefixime and Ornidazole find up to be 5.4 ± 0.2 min, 3.2 ±0.4 min, and 0.60% and 0.65%.  The % RSD Obtained for Cefixime and Ornidazole were 0.60% and 0.65%. LOD, LOQ & Assay encounter ultimate integrity will be acquired from the Cefixime and Ornidazole were 0.80 ppm, 0.81 ppm, 2.25 ppm & 2.22 ppm, and 101.04% and 100.41% respectively.

Keywords:

Analytical Validation, Simultaneous Estimation, RP-HPLC Method, Limit of Detection & Quantification

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Published

2021-06-11

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Original Article