International Journal of Clinical Pharmacokinetics and Medical Sciences <div> <img style="width: 100%;" src="" /></div> <p align="justify">International Journal of Clinical Pharmacokinetics and Medical Sciences <em>(IJCPMS)</em> ISSN: 2583-0953 is established in the year 2021 officially sponsored by <em><strong>pharma springs publication</strong></em>. We are pleased to introduce ourselves as the novel imminent, and sovereign online pharmacy &amp; medical information services in India. The foundation aims to serve as a means for updating the scientific knowledge of the international audience in the research field of science so a correlation can be made between these researchers. IJCPMS will be published quarterly per year in March, Jun, September, and December. The journal publishes the work that contributes significantly to further the scientific knowledge in the areas of pharmaceutical, medical &amp; biological sciences. All contributions to the journal are rigorously refereed and are selected based on the quality and originality of the work.</p> en-US (Editor) (Editor) Fri, 24 Dec 2021 00:00:00 +0000 OJS 60 A Case Report on Lymphedema <p>Lymphedema can be a regarding approach about a disorder throughout the vascular system for which explanations femoral lump. Defective ingestion, as well as transportation containing lymph fluid via lymphatic vessels, cause accumulation of protein-wealthy liquid during interstitium, which results in traumatic inflammation of the overall femoral. Underived lymphedema will be regularly nominative at delivery. The rare instances that fact take the floor succeeding historic period 35 years will be terminated as lymphedema tarda. The amazing clients along with edema experience lump going from the decreased limbs top femoral edema will be a group a rare ailment. A 76-yr-old person was once provided along with type a 3-year record containing unilateral lump going from the leftover top limb.&nbsp; Would have been no constitutional indicators as well as no test copy of lymphadenopathy or fundamental skin disorder. Blood exams, carcinoembryonic antigen viva, computer-assisted tomography scans, and venous Doppler ultrasound had also altogether ordinary. The overall trend analysis becomes primary higher femoral lymphedema. The lump that happens in the upper femoral lymphedema is often unchangeable and generally expands up to the hand. Almost 1/3 of those who are victims of the aliment herewith state seem to be treated as well as decreased limb lymphedema. Investigations are going to be allowed in incidents containing unilateral top limb lymphedema to prevent hidden malignancy and intrinsic complaint.</p> Pandala Archana, Annabathula Meghana, Hawashetty Priyanka, Marella Priyachandana, Allu Sree Reddy, Mogulla Soujanya Copyright (c) 2021 Fri, 24 Dec 2021 00:00:00 +0000 Lissencephaly with CMV Infection: A Case Study <p>A nine months old baby boy was admitted in a pediatric ward at SGG Hospital, Vadodara diagnosed with lissencephaly associated with Cytomegalo virus (CMV) infection. Lissencephaly includes severe brain deformations. Cytomegaly infection is popularly known as a pathogen for this anomaly. He had both Computer Tomography scan and Magnetic Resonance Imaging tests. A social smile was absent and he was previously diagnosed with Global Developmental Delay (GDD) and a deformed head. Congenital Cytomegalo infection (CMV) is a vertically transmitted disease in newborn infants which causes multiorgan affection. But the most severe and permanent damages are those affecting the central nervous system (CNS) such as mental retardation, sensorineural hearing loss, chorioretinitis, cerebral palsy, and seizures as a result of the virus with neurogenesis.</p> Shring Sandilya, Amit Sarkar, Tousif Idrisi Copyright (c) 2021 Sat, 18 Dec 2021 00:00:00 +0000 A Prospective Observational Study on Prescribing Patterns of Anti-Hypertensive Drugs in Patients with Hypertension <p>A prospective observational study was carried out among 180 patients for a period of 6 months at in-patient department of cardiology, Apollo hospital. A total of 180 prescriptions with different co-morbidities were enclosed in the present study who met the inclusion criteria. 63% were male and 37% were female with mean average of 36±23.16. 34.4% of the patients were in the age group of 61-70. The common co-morbidities along with hypertension which were seen in the study are diabetes mellitus (38%), coronary artery disease (31%) and chronic kidney disease (9%). The most commonly prescribed therapy was monotherapy given in 116 patients (64.4%) followed by dual therapy given in 59 patients (32.7%) and triple therapy was given only in 5 patients (2.7%). Among the monotherapy, the various class of drugs prescribed were ARB (34.4%), followed by CCB (32.7%), BB (25.8%), ACE inhibitors (3.45%) and B+A (3.45%). Among the dual therapy, the various class of drug combinations prescribed were ARB+CCB (28.8%), followed by ARB+Di(22%), ACE+CCB (20.3%), CCB+BB(15.2%), ARB+BB(11.8%) and CCB+Di(1.69%). In triple drug therapy the various class of drugs used were ARB+BB+CCB (60%) and ARB+Di+CCB (40%). In the present study, it was found that monotherapy was the most commonly prescribed regimen followed by dual and triple therapy. ARB was the most commonly prescribed class as monotherapy, ARB+CCB as dual therapy and ARB+BB+CCB as triple therapy. In monotherapy, commonly used drug was telmisartan. In dual therapy, commonly used drug combination was telmisartan+amlodipine and in triple therapy, commonly used drug combination was telmisartan+metoprolol+clinidipine.</p> Neha Singh, Yashwanth Podeti, Sumayya Hussain, Samreen Fatima, Sujala A Copyright (c) 2021 Wed, 29 Dec 2021 00:00:00 +0000 Assessment of Drug Related Problems in Cardiovascular Diseases and Prescribing Patterns of Cardiovascular Drugs in a Secondary Care Teaching Hospital <p>Cardiovascular diseases (CVDs) are a serious public health concern that has risen to become the leading cause of death and premature death around the world, as well as a major contributor to rising health-care expenses. This study aimed to assess and determine the prevalence of drug related problems in cardiovascular disease patients along with identify prescription pattern of cardiovascular drugs during course of treatment in our study population. Prior authorization was received from the Institutional Ethics Committee. This prospective observational study involves 160 hospitalized patients in the in-patient department of a secondary care hospital. The prescribing pattern was analyzed and assessed during the period of 6 month and drug related problems in the following patients were reported. Of 160 patients, 102 (64%) were male and 58 (36%) were female. Subject of age group of 61-70 (n=51) were found to be more suspected. A total of 160 cases identified 366 DRPs. The most common identified DRP were the DDI 281 (77.41%), polypharmacy 42 (11.57%), no lab data or lack of monitoring 14 (3.82%), indication without drug 7 (1.91%), drug duplication 5 (1.36%), drug without indication, contraindication and ADR 3 (0.81%). The most common DDIs was aspirin + furosemide (n=23). The most offending drug involved in DDI was observed to be aspirin. Most of the prescription were prescribed with ant-platelet agent (41.22%), statins (15.71%) followed by CCBs (7.47%). Prescribing pattern of drugs in cardiovascular diseases concluded that optimized drug therapy lead to minimal ensuing DRPs. Clinical pharmacist recommendation in prevention of many DRPs can reduce the disease complication.</p> Georgina Sarah, Sithara S, Anisha Varghese, Jagruti Pashte Copyright (c) 2021 Sat, 18 Dec 2021 00:00:00 +0000 Assessment of Knowledge, Attitude and Practice Towards Dengue Among the Selected Areas of Kalaburagi City <p>Dengue fever is a viral disease that is occurred due to mosquito which is a one among huge global health issue as it is spreading all over the world rapidly. Every year, September and November are the months that shows peak incidence and annual outbreaks are reported in these months. Considering the year 2014, there are more than ten thousand dengue cases reported in India that has been double to the following year.&nbsp; A total of 600 individuals were enrolled into the study, out of which 586 people completed the study of which 239 i.e. 40.78% were male and 347 i.e. 59.21% were female. The remaining 14 individuals did not turn up of for follow up and were under dropouts. The data of those who completed the study was analyzed. A total of 586 people were included in the study, who were divided randomly into test and control group. Out of 586 people 293 were in test group and 293 were concluded as control group. In test group out of 293 people 121 i.e. 41.29% were males and 172 i.e. 58.70% were females. In control group out of 293 people, 118 i.e. 40.27% were males and 175 i.e. 59.72% were females. In present study a total number of 586 people were enrolled in the study. The total population was randomly divided into test and control groups. 293 subjects were included in test group whereas 293 subjects were included in control group. We have provided counseling in their respective language with patient information leaflet(PIL) and the results revealed that counseling by pharmacist rely helped in understanding the disease, medications and preventive measures. The result revealed that there is increase in KAP scores of the dengue due to the intervention made by pharmacist. Hence pharmacist plays an important role in community set-up by educating the people regarding dengue and controlling the forthcoming complications of the diseases.</p> Matapathi Hermonica Rose, Gubba Gayathri, Kesaram Sravani Reddy, Sharanabasava S Biradar Copyright (c) 2021 Sat, 18 Dec 2021 00:00:00 +0000 Estimation of Risk Factors for Computer Vision Syndrome and Impact of Clinical Pharmacist <p>Computer use has become ingrained in our daily lives. The increased usage of computers has resulted in an increase in the number of people suffering from ocular symptoms that have been labelled as computer vision syndrome (CVS). It's impossible to pinpoint a single etiologic element that produces computer vision syndrome; instead, it's a complex mix of factors. It is a prospective, interventional study conducted on online carried out from December (2020) to may (2021). Data collected from online Google forms and the sample size enrolled in the study was 236. According to our study we come to know that males (62.1%) are more affected than females (37.9%) and 20-30 years age category subjects are more affected than 31- 40 years and also students are more affected when compared to females. The most common symptoms the most common symptoms that we observed in our study are eye burning, eye itching, watery eyes, blurred vision and dryness of eyes all these are ocular symptoms. Among extraocular symptoms most common are neck pain, back pain, headache, shoulder pain. The responses what we received are 236 members out of these 97 members are lack of knowledge while handling the computers, so after those who are having poor knowledge we provided a patient information leaflet and suggested them to follow the tips for 28 day period. After 28 day period 75% of the computer users gained knowledge.</p> Bygari Sathyanarayana Reddy, Amasa Anusha, Nallasiddu Sushma, Singareddypalli Nagabuushanachari Yogesh, Leela Prasad Babu K, Chinnikrishnaiah V, Swarnalatha D Copyright (c) 2021 Mon, 27 Dec 2021 00:00:00 +0000