Gold Nanoparticles: A Review

Authors

  • Sujatha S Department of Pharmaceutics, Narayana Pharmacy College, Chinthareddy Palem, Nellore - 524003, Andhra Pradesh, India
  • Rabbani Sk. Department of Pharmaceutics, Narayana Pharmacy College, Chinthareddy Palem, Nellore - 524003, Andhra Pradesh, India
  • Sai Teja P Department of Pharmaceutics, Narayana Pharmacy College, Chinthareddy Palem, Nellore - 524003, Andhra Pradesh, India
  • Kishore Kumar Silesian University of Technlology, ul. Akademicka 2A, 44-100 Gliwica, Poland

DOI:

https://doi.org/10.26452/fjphs.v2i3.284

Keywords:

Gold Nanoparticles, Photothermal Effect, Cancer Cells, Targeted Drug Therapy

Abstract

Gold nanoparticles are small gold particles with a diameter of 1 to 100 nm. Their characteristic surface Plasmon resonance feature aid indistinctive absorption and optical properties which can be characterized and can be useful in many biomedical applications. Gold Nanoparticles can be used as delivery vectors due to their high surface loading capacity of drug, gene, Protein or vaccine. The surface of Gold Nanoparticles can be modified by molecules such as polymers, Ligands, surfactants by conjugation increases its ability to cross the membrane and also helps in reduction of cytotoxic effect due to attraction to targeted areas. So, it can be used in Targeted drug Therapy by conjugating cancer drug molecules to these particles. Gold Nanoparticles absorbs certain wavelength of incident light and converts into heat which is transferred to cancer cells and leads to destruction of cells due to photothermal effect.

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Published

2022-07-11

How to Cite

Sujatha S, Rabbani Sk., Sai Teja P, & Kishore Kumar. (2022). Gold Nanoparticles: A Review. Future Journal of Pharmaceuticals and Health Sciences, 2(3), 196–202. https://doi.org/10.26452/fjphs.v2i3.284

Issue

Section

Review Articles